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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c4d023501429d0bea492ee2da07f06d66119dc4551c575e0c90ddc53ac364c0' 
  AND token = 'tX6bjoOHilcMn412nCh6pj1EqEbjXXXTcW/xaEXf1Nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}