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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2c7bb6f63632dcd8861d80a8d160f15138c546edddbf976332abd8178b6b9c3' 
  AND token = 'x/cxt9Sb8g6tAN5XQ3P9oipI0ll8NHlSrIYVNpwFM1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}