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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c180df73b70fe55c5a7fb4680a486ee5c59fd34fe499b593afc7f5e70504b42d' 
  AND token = 'eGcTfWL09iBk1JpI5CccOMwrCnpv9qeNCd0YDUa9OfY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}