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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a9548d71b1d2afccdf6f8a0fce6cf2fad465ef41363af2b8ca07351139aa604' 
  AND token = 'fN3ikV5UA5Npsv5vv+qMb6w2j73FLrgmNNdGk56m73w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}