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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23e5aebef239b2380693e9b1425a9c152c1bd80778e27bf56b2c932d4a1f7005' 
  AND token = 'Sd71is6ERwmLRCeZG90Mh3RFJYqLIpBKNGiyX8qAp/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}