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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19a261e546226d47f3c7894d8288c37f3355264a8dd29e7a88cae7241f508a23' 
  AND token = 'n9E+oqEFzbC8p0hokNAAeBA2DVp7uYCGg2kA8+GyOWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}