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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e183cda4be986916af934939f8eca086f08a8877c844ea04d57308fa953534f' 
  AND token = 'kiEk50dvlpNd3HRygve1nuUx3t3k1ugWv6J7Nzl8NGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}