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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8df1114ec9a06d89d86039258b5f916fb06297417b8fb4aec6dcf87bcf0efc77' 
  AND token = '2GJ9osW/S9gP6STu76Q44XHr7AeSKuaOUCastzbE8FI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}