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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b9fe3f88511a38905b07e8b95806cb8d13b2964e63c628498f7a2e1cd108c35' 
  AND token = 'NszT/Vu7t0OgfJYhN2JfY0aN5pT8prLOF9vukrmZRJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}