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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8441f6733436a2c286ca446a24d3ef2bc9238bd1387defb1247bfff2aa79eec4' 
  AND token = 'Ni2W5ibxvSR3t2wy1mRA9/E1veQicT9fIWNNPEpkQnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}