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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f1f1d30c7cda9991d39ada6a29787d75db739dcc1e28c057e7954a20106f8b8' 
  AND token = 'ekMY32E/ZcgfP/A1/yGNgGpi+v2bn3exrlcqHsaSd+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}