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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1b41559a045ef8225e5c14c77bbaed2a5fd825d6791a26a7df5fd84b08c135e' 
  AND token = 'XY3Gf2gVr4aghfMcNtiC8kj/B0Cbn41U5EPTZyt1ruM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}