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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac18c007f0f3b3250cdcbbe413cc9db8d206f153c9a742c02bb203ed39d76d75' 
  AND token = '/K7gmnHlyGCpHeEuw7cd8bZESOfGgfcqXL6Hy5PXAxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}