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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '906c80846cb4696eec2a4e4d4f20d9b7f3546bfa6b961f02406eeabb314fdcd6' 
  AND token = 'aK31b2qOfZ7t/QVA5g+dQTKUDZHiQjZR/23TWVNN5vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}