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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fbe6f990125046da0839765ec3fc2b541a1bca1ffafbcc4bc7d18e5d60ceb57' 
  AND token = '8z04DxrKxYT4uca1pR+CGwmW+f+qsST082XtAOY6fjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}