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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b2a244ae88a30c9d5e0f9ac16d772499c5980c56e28863e68bfa26c7fd459e3' 
  AND token = 'COA3D4ltt/0y6u56jj8lSz4KBzihebxKie30qVOwEzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}