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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3aa59672c4ea2e4ef6200c7857a82c91f80ee9315f1af1d2ff26e61285b42f66' 
  AND token = 'tWyzy0LMKo3hGdrjmi0PF9NPel2sT8+fGhX2iCtyd4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}