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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dff320077aa5748a796f2f5059b10b1e070b376262db8d58d5e9df7c7b04330' 
  AND token = 'hrg8NQMjLkpLCrGpf4uF+djVXV/bUUmuTTkjhGmp3Hk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}