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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bac6521ca9c565eaffd81afcb00c74020a68680ef58d7bf38aeff3a2e41c21ea' 
  AND token = 'vvtaDkk0UgTUeq/+qKE6gmsWHNmoVhipUdKMNk0CyJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}