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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3cdc88fdf840d97710570624bbb09f3b873d852d5e178001bab91f5ec090f3c' 
  AND token = 'cSZWByPla94QxIz4Oe6KLH20GkyH0T+hHbYzjB27ecI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}