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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f0c375abffd332175c221e227b3f4beeb7b0dc73bd5d7f921ce14f10d6a0da1' 
  AND token = 'A0YQXIqIZ0Bpv/5io5m4gtgSNwfYFSQl4wQwel7B3Rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}