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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce8e74177b7fd2c1af09b03a165c6a293b91dc1c4255306a494f624008f81f54' 
  AND token = 'WY3dbmvYDgsSovgMMGh+qNDRs24pmkjely4hOxmZ7MM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}