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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26c02ecaa3fc044d9145ad0c8c36c00bd737af7bcca387ca003c27e3ee1a70c8' 
  AND token = 'eWT46RE+i54t2rInqJ6r2I0/002pgV9Uh4sHhvYaeAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}