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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6460cc8d6e2be0fcdc67f38f1b5080b713e68e1a78284c317b6fa96f0757b5fb' 
  AND token = 'kSWfiCRSDnJ1hVJ2vVj75/5KsH0EEGXAbpO11KrNAQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}