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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71cc0136dcd0e5964cfa56a040dbd477a946fd686daed3cc8cee2af6bb535492' 
  AND token = '5O05mfcWMPj6Z0bmB9I6ViaQw1/wlyrWp+UK1C0H9Xs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}