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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd19678117b08c7189591ac005ccedd309b619b196485b0c21c5c0a7bbb90ba7' 
  AND token = 'wT1AY9R9gymEx9EF+7SU8EGW1fMXOtRbVViwC2p1QUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}