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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6acb514b809f60583d1787f814806593a667c42a00fe1f9dcba1917b8e97981' 
  AND token = 'fncQ15rx+FsWkdFaiPVvH+TCPMT0CYaCNHsOtVZajlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}