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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd78b9cc0fa20111cfddaf07cab9dd4a4c891e802794a7e9e1acaea42ef21278' 
  AND token = 'VL30Oz4NPoVxSLEhJZrHjxo3nlI0FB1rFp3g2S6Obd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}