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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e287360ebc34a773293150c438969080f599c36b469ecf74c65094c913d634f' 
  AND token = 'Y6jmiGDfpW+GYhwpojjYWVevdbigs4XU7f82F2dNxbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}