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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04d2f0159fe536f06c67158fb6b78023926c1c351ed6c7bd016ec14bc6051c78' 
  AND token = 'R0Tf40j5aajVNG/EL/ohJ/7xTlLcPjVuVA3MTozIL9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}