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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '029548f93890d85207b9cbcc030026bf73b48a3c3190e72153dafee39709c648' 
  AND token = 'U/NKcEPDEMckz99OcRx5PGiCToylZxon7ALu6UFJ5cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}