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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39a8c9e160d0486f2e0e746b432e3c0a32ed2b676c3e8739291643e00fa258ed' 
  AND token = 'JghKzAk4gz9/XrMAM5mWVgFIxGLbXme1z6LLv7Kvj0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}