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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c5dec0398e32e4f6d47236be660c351a9dbc52c2b870c06825d296a7782915f' 
  AND token = 'I35r0cnZWDg1aNWwyrD6hUzB/TvNOYyMRtlRwrZGw/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}