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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a06b106f200f4194429f3910d1ed0ee5917b58e52b25dbfb148c1cb53ddb04b' 
  AND token = 'LBvMpqAfoQpcj9nXiZcMBWLRfxXiHIaiqYnGGz6PUzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}