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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45424b01c6f6ac7ad20379a53f1cb4210a52a11d94f3b7827798c3cb7f48de28' 
  AND token = '3RmeurHay1O5Zk2GaF7mtSOKAxisVbLAN+6+sWlGGDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}