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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '633d42717fb52b3b1cb03d5b370d2379bda437499cc7d4fdf409b063a9abfcfe' 
  AND token = 'Sl5zWPKWpTHOvc/4hMpW9MZHFIBBFGnvotmiKTWUnQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}