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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '774e4ca782bba75e8ec68351553b3babde557affe80b80800979ff3e3b9c3ca5' 
  AND token = 'uZjWAavWs/NZfbcWjkcxCimLeodCULyKB8ZMd4qNkrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}