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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b53291347475ff0f6eaef7715ab3e4145341af58020bbef9301fe0675b73a213' 
  AND token = '33kv6A2OR36/yhMs1jo0uElAhPBpPEuDBUNfEBdgfMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}