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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf3cf9970f40c38de2edf8d7f00058731bd1489457b24c0a5d731ef664740523' 
  AND token = 'hlLmUfnG2srHyDL+w7v+b+HyMA7oNHBDDaY+3f508fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}