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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01b36a09b13d46cb12182501d9ebbc494dab80457b5b41032f64615541463a22' 
  AND token = 'bXbf6F8jaqUEvjcC/BS31QO7K9pVHXv+srI9VePaNhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}