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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c97a42957d7c9d8680c9d44961fb9979da13d408c19e1b6fcb4cecbcc8bde50' 
  AND token = 'fLq/76WpjYkBxaY7YHEOQN4MnNRIj3w5pX1rwdGmD6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}