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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b689c98a47ffa45e950a0b016aa6ee38f582f01a3819ddbb2e2fd0152d92470' 
  AND token = '7tNpPzchmaGGhrr6iB6e6NEWznRIhhnBHuF3JM4NBzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}