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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04e05f5ec2f9d254f63380e5f1286b03106a9f69b741f1f2d49c213a772282c2' 
  AND token = 'x6IcKOfrRQIhiHb3NqH7HqSw/ursfEm77YF2YOC3tQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}