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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '944820739206fdc659ed87a24122132e8d28cc5ea17f7635c672bfb413643dfa' 
  AND token = 'dnTwmwI6tQv3+wkVlDoVO4rd3BySqgGF2Q+9GkN9bWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}