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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e5c1dcb8e3242ce7c5ab3ff0b803e2072dff05194a3bf137882d5558e01512a' 
  AND token = 'zGbRT2blNWRy+UJd3XlMy5L4EFwDkKLLq6hbn4vM3DY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}