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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f648068d9aaa0ba20517befd7ccfeb0cec09c6699ec224d807e44bfd90dd252e' 
  AND token = '+y4KrbZnCgbQDm+zQL6Af7BH94tSW8QAU7SqGVTmBtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}