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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33d65045cc8c20e8363df579118ffd4d6af2cb3fa829a3ad89e74d3675ab6749' 
  AND token = 'yIX+42Rjys+kdR/zq78O1aCJtyBM/1jUgKA8cgT+qW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}