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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccdfd4f383dead791c3c1fed7c1fd8cad1594cfed69483f94131239c2c563c85' 
  AND token = 'p21h+Z42f7XEdzIFHY3Ydih4doE3h1N21gkLeNaWCjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}