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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71224f78adc82e572b230a105bc32f958332e73485f2e3638b34f2d30d8ebd1e' 
  AND token = 'Y0OnBxKJgsLzlj75oS03Q9Qv0l+QjCQsvzgEJE7gT0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}