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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71ff2f3e1926f3fa31974ca48e8047fca590e42a646e9a907432c796a2b13e7a' 
  AND token = 'cqhMWSBPsMKrVEUFm6U+P/xqybIWvX8WacCyvE1Qi0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}